DNase I

(Recombinant, RNase-free)

High-purity endonuclease for efficient DNA digestion in molecular biology and advanced bioprocess workflows.

DNase I

(Recombinant, RNase-free)

Synonym(s):

Deoxyribonuclease | Deoxyribonucleate 5′-oligonucleotido-hydrolase

General Description

DNase I, (RNase-free) is an endonuclease that nonspecifically cleaves DNA to release di-, tri- and oligonucleotide products with 5´-phosphorylated and 3´-hydroxylated ends (1,2). DNase I acts on single- and double-stranded DNA, chromatin and RNA:DNA hybrids.

Highlights

Expressed in recombinant host system

Product Source

High-yield GRAS fungal expression platform

Applications

  • Genomic DNA removal from RNA workflows
  • DNA digestion for sample preparation
  • DNA template cleanup in transcription workflows
  • Viscosity reduction in tissue and cell processing
  • Controlled DNA digestion for analytical applications
  • DNA removal in gene editing and synbio workflows

Properties

Product Name DNase I (Recombinant, RNase-free)

Source

Recombinant expression system

Enzyme Type

DNA-specific endonuclease

Substrate Range

Single-stranded and double-stranded DNA

Purity

High-purity preparation

RNase Contamination

None detected / RNase-free

Format

Lyophilized powder or solution
Recommended Storage

-20°C

Intended Use

Research use | industrial workflow support as applicable

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